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In 1928, Sir Alexander Fleming returned from vacation to find that a petri dish of Staphylococcus cultures had been contaminated — an accident that led to the discovery of penicillin. Ninety years later, in 2018, Japanese scientists accidentally altered an enzyme and found it could break down plastic significantly faster. What connects these seemingly unrelated moments isn’t meticulous adherence to the scientific method. These “happy accidents” weren’t born from controlled, procedural experimentation. Instead, they reflect how scientific breakthroughs often emerge from veering off course, driven not by protocol, but by the curiosity, intuition, and creativity that define human discovery.

WATCH NOW: An exclusive conversation with Alumni Venture’s Strategic Tech Fund and Matt White, Co-Founder of Multitude Insights

MANCHESTER, N.H., July 28, 2025 – Alumni Ventures (AV), one of the most active venture-capital firms in the United States, today announced that it has joined SEI Access™, SEI’s end-to-end digital marketplace for alternative investments, expanding the venture-capital options available to eligible RIAs and fiduciaries. The addition gives RIAs streamlined access to a professionally managed, highly diversified venture-capital portfolio within the same workflow they use for other private-market solutions.

Delivery is only part of the challenge and risk. That’s true of both the pizza business and healthcare. That insight hit hard at our HealthTech Pizza Tasting during NY Tech Week. With founders, investors, and operators gathered around, we considered key questions. Who’s ready to own the next big slice of risk? What slice of healthcare risk is actually worth owning? And when is one slice better than the whole pie?

Picture this: It’s 9:37 AM on May 14, 2025, and you’re standing in the New Mexico desert watching a small rocket lift off from Spaceport America. What you’re witnessing isn’t just another engine test: it’s history in the making. Venus Aerospace, led by Sarah “Sassie” Duggleby, just achieved what many thought impossible: the first U.S. flight test of her company’s Rotating Detonation Rocket Engine (RDRE). This compact, highly efficient propulsion system is designed to enable hypersonic flight — and redefine how we move through the world.

Courtrooms are slow. Contracts are messy. The workflows? Still rooted in the ’90s despite a few giants like Harvey entering the space. But this won’t be a winner-take-all market. A foundational shift is underway in the legal sector — driven by generative AI, rising cost pressures, and a new wave of founder-led innovation. From deposition prep to document review, automation is no longer a buzzword. It’s shipping and starting to scale.

The past five years have been brutal for cybersecurity leaders. The 2020 SolarWinds breach showed how nation-states could weaponize software supply chains, compromising thousands of organizations across public and private sectors. In May 2021, the Colonial Pipeline ransomware attack shut down nearly half the fuel supply for the U.S. East Coast, triggering widespread gas shortages and panic buying. Just a few months earlier, vulnerabilities in Microsoft Exchange gave attackers access to tens of thousands of email servers worldwide.

Last week, more than 1,500 investors squeezed into a San Francisco venue for a coveted seat at YC’s invite-only Spring 2025 Demo Day. Over six hours, 144 startups delivered rapid-fire, one-minute pitches, each launching just seconds apart. Investors furiously took notes, sized up founders, and fired off intros. Yet Demo Day has evolved beyond a pure deal-sourcing frenzy. By the time the curtain rises, many YC teams already have term sheets in hand from top firms and are well on their way to sealing seed rounds.

At The Greenwich Economic Forum’s inaugural London gathering, three entrepreneurs sat down to discuss what it really takes to build a company in today’s global landscape. What emerged wasn’t just another panel about startup success stories — it was a candid exploration of the fundamental challenges that define entrepreneurship across different markets, stages, and sectors.

Join Alumni Ventures’ Brian Keil and Hilary Ncala for a practical and informative session designed for new investors.

For those looking to understand venture investing, a case study can be the best place to start. At AV, we learn by looking back at both our stellar and less successful deals. In the case of our investment in Oura, the story is one of strong conviction, strategic timing, and a company that continues to exceed expectations.